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See Nexus 128+ in action.

Nexus 128+, the only commercially available fully 3D photo-acoustic imaging system, provides increased sensitivity, isotropic resolution, improved image quality, faster scan times, and higher throughput for molecular probe uptake, tumor imaging and spectral analyses.

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Probe uptake and distribution

Uptake of a NIR probe in a subcutaneous PC3 tumor over a 3hr period post-injection. The tumor was scanned at 760nm for 2min at each of five time points. Images are displayed in OsiriX image viewing and analysis software.

Probe uptake and distribution

Uptake of a NIR probe in a subcutaneous PC3 tumor over a 3hr period post-injection. The tumor was scanned at 760nm for 2min at each of five time points. Images are displayed in OsiriX image viewing and analysis software.

Tumor vasculature

3D, Maximum Intensity Projection (MIP) rendering of blood vessels encapsulating a subcutaneous fibrosarcoma following i.v. injection of Indocyanine Green (ICG). The tumor was scanned at 800nm for 12 sec.

Tumor vasculature

3D, Maximum Intensity Projection (MIP) rendering of blood vessels encapsulating a subcutaneous fibrosarcoma following i.v. injection of Indocyanine Green (ICG). The tumor was scanned at 800nm for 12 sec.

Fast, dynamic imaging

Video depicts the uptake of Indocyanine Green (ICG) in the vasculature of a subcutaneous PC3 tumor and surrounding tissue over a 3 minute period. Full, 3D volumes (25x25x25mm) were acquired every 3.5 seconds.

Fast, dynamic imaging

Video depicts the uptake of Indocyanine Green (ICG) in the vasculature of a subcutaneous PC3 tumor and surrounding tissue over a 3 minute period. Full, 3D volumes (25x25x25mm) were acquired every 3.5 seconds.

Multispectral imaging

A tunable laser (680-950nm) and high sensitivity allows users to perform spectral analyses of novel probes and contrast agents ex vivo or in vivo. The video below shows a multi-wavelength display of a subcutaneous tumor following injection of a NIR tumor-targeting probe in vivo. Images were acquired at seven different NIR wavelengths (12sec per scan) and displayed in OsiriX image viewing and analysis software.

Multispectral imaging

A tunable laser (680-950nm) and high sensitivity allows users to perform spectral analyses of novel probes and contrast agents ex vivo or in vivo. The video below shows a multi-wavelength display of a subcutaneous tumor following injection of a NIR tumor-targeting probe in vivo. Images were acquired at seven different NIR wavelengths (12sec per scan) and displayed in OsiriX image viewing and analysis software.

Dual probe uptake in areas of low and high perfusion

Demonstration of ENDRA Life Sciences' Nexus 128+ photo-acoustic scanner showing the rapid uptake of near infrared molecular probes in a mouse tumor model.

Dual probe uptake in areas of low and high perfusion

Demonstration of ENDRA Life Sciences' Nexus 128+ photo-acoustic scanner showing the rapid uptake of near infrared molecular probes in a mouse tumor model.